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EBNA-3a–deficient LCLs proliferate far more slowly and demonstrate amplified apoptosis as compared to wild-sort virus–derived LCLs.
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These conclusions posture EBNA-3a similar to a vital modulator of B cellular proliferation and survival through EBV latency, and as a applicable CD8⁺ T mobile purpose in the two uncomplicated immunological experiments and translational look into.
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